Updates log
Study links and recruitment status updated
- Added a prominent link to the official SONIX study website on the SKY-GJB2 study page.
- Updated the SENS-501 Audiogene study to Active, Not Recruiting based on its current ClinicalTrials.gov record.
SKY-GJB2 surgical record clarified
- Updated SKY-GJB2 to show transcanal endoscopic tympanotomy with round-window access.
- Recorded that no additional fenestration is reported in the official SONIX and participating-site trial materials.
- Linked the official SONIX study website and Lehigh Valley Health Network trial page to the supporting surgical fields.
Homepage and Studies comparisons expanded
- Added countries, vector, promoter, and fenestration details to the homepage clinical-program comparison.
- Added distinct row colors for OTOF and GJB2 programs.
- Updated the DB-OTO surgical approach to include round-window membrane injection and lateral semicircular canal fenestration, supported by the program-specific human publication.
- Increased the Studies table text size, added countries, and introduced gene-specific OTOF and GJB2 pills.
Study eligibility and regulatory details clarified
- Added FDA approval status to the clinical-program comparison, including the approval date and source for DB-OTO.
- Delineated the AK-OTOF-101 cohort age requirements and clarified the EH002 minimum age.
- Simplified the Evidence Registry introduction and terminology.
Evidence Registry added
- Added a source-level evidence record for every clinical program.
- Added study start dates to the program comparison.
- Revised the homepage language to describe the registry scope more precisely.
Evidence review protocol expanded
- Added a repeatable literature-mining protocol for information not available in ClinicalTrials.gov.
- Marked details that could not be verified in a program-specific public source as “Not publicly disclosed.”
- Reduced promotional language and simplified the homepage information hierarchy.